The study: In an Australian study, a panel of 101 adults with knee osteoarthritis, was chosen on a randomized double-blind basis. An 8-week study compared a standardized curcumin extract (Curcugen®) to a placebo. This study measured the Knee Injury and Osteoarthritis Outcome Score (KOOS), knee pain ratings, Japanese Orthopaedic Association Score for Osteoarthritic Knees (JOA), PROMIS-29, and performance-based testing including a 40-m fast-paced walk, a 6-min walk, timed up-and-go test, and a 30-second chair stand.
The results: KOOS knee pain rating scores and numeric knee pain ratings were significantly reduced by turmeric (p 0.009). Also, curcumin improved timed up-and-go, 6-min walk, and JOA total scores better than placebo (p 0.05) Compared to the pain medication’s 37% improvement, curcumin managed to reduce pains by 13%.
Consumers also reported experiencing less stiffness in their knees and joints with normal dosing.
In Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) study, an extract group that took two capsules by mouth three times daily after meals experienced significantly fewer abdominal pain/distention adverse effects.